Regulatory compliance of pharmaceutical process

Ontoreg is a computer-based decision support system to assist in the identification of regulatory compliance of a drug manufacturing process. The system encapsulates the pharmaceutical process and regulation knowledge in two complementing representations: OWL ontologies and SWRL rules. Our approach has the potential to decrease the pharmaceutical process validation time and effort which will reduce the development costs and commercialisation prices of future medical products. Furthermore, the novel approach has the potential to be extended to other regulatory applications in the future.

Rationale management and multi-criteria decision analysis

The objective of this research is to create tools which facilitate, clarify, record and accelerate decision processes in a dynamic and flexible environment. While the program can be used for any decision process, it is being developed with specific features for energy policy development. The research centers on the extension of Compendium, an open sourced public-domain ‘dialogue mapping’ tools that allows the user to represent visually concepts, ideas and arguments via nodes and links between them.

Semantic Representation of Energy Policy Goals related to Electricity Generation

The objective of this computer model is to mimic the considerations given to and influence received from geopolitical and social factors within the energy policy formulation process. This is achieved through the development of an ontology-based decision support system to represent the energy policy knowledge domain. The knowledge domain is modeled on the principles of Ontology and the heuristics is based on First Order Predicate Logic with rules for Higher Order Logic Functions. The model offers automatic mathematical expression formulation through the use of knowledge inference. Inferences from the model is validated for implementation feasibility by a mathematical-based set of engineering models which represents current energy generation technologies.

Tool for evaluation of water treatment plant

The tool at this stage of development: (i) identifies three sites within the study area that are an appropriate place of construction for the waste water treatment plant, (ii) identifies the least cost path for sewage pipelines to these WWTP sites, and (iii) compares the cost of sewerage system of the centralised real case and that of the hypothetical semi-centralised system. The tool is an integrated framework that creates interoperability among the specialised platforms (Mathematica, Python, Java, MySQL) .