Dr Athina Markaki Dept. of Engineering, University of Cambridge

Stainless Steel Fibre Networks : Mechanical and Cellular Responses
When Feb 11, 2013
from 02:00 PM to 03:00 PM
Where LR8
Contact Name
Contact Phone 01865 283302
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Porous implant surfaces favour bone anchoring. Porous coatings (>50% porosity), made of metallic fibres, were first proposed in the early 70s to improve the mechanical interlocking at the bone-implant interface via bone tissue growth into the inter-fibre space. In addition to the capacity to provide space for infiltration, first by cells and ultimately by osseous tissue and vasculature, beneficial effects on bone-implant bonding may accrue from fibrous networks which deform in vivo and generate internal stresses/strains within the in-growing bone. This design draws on the concepts of strain-regulated bone modeling and remodeling. The presentation will focus on fibre network materials made of stainless steel and, in particular, on some aspects of our recent work on (a) measuring the elastic constants and fracture characteristics and (b) the mammalian cell responses to different topological and chemical environments.