Department spinout company wins New Product Award for microscale benchtop technology

iotaSciences, a spinout company from the Department of Engineering Science, recently received a New Product Award at Society for Laboratory and Automation Screening conference SLAS2018, in recognition of their innovative and portable benchtop single-cell instrument, the isoCell.
Department spinout company wins New Product Award for microscale benchtop technology

A microGRID side view

iotaSciences is focussed on developing and delivering solutions to life scientists and the biomedical sector based on innovative fluid shaping technologies. The company was founded in 2016 to commercialise a fluid-shaping technology developed by engineers and scientists from the Department’s Oxford Thermofluids Institute and The Sir William Dunn School of Pathology.

iotaSciences have developed isoCell, which utilizes this proprietary fluid-shaping technology to create small-scale liquid chambers (microGRIDS) and deposits single cells into them. The system overcomes a main obstacle in assuring the monoclonality of cells by replacing solid walls with fluid ones and hence providing excellent optical clarity on any microscope, allowing researchers and labs to analyse single cells in a very cost-effective way.

The isoCell system should have a range of academic and medical applications, including accelerating the research and discovery of next-generation therapeutics, genome editing, production of monoclonal antibodies and protein therapeutics, and the establishment of novel cellular disease models.

Joey Riepsaame, Head of Genome Engineering, Sir William Dunn School of Pathology, University of Oxford, explains how the new technology benefits his research: “we need to generate many different gene edited clonal (stem) cell lines. However, isolating and expanding single cells is a very long and labour intensive process that can take up significant resources. IotaSciences’ isoCell allows us to bypass these issues and facilitates the generation of clonal (stem) cell lines with minimal hands-on time while considerably reducing the amount of consumables.”